Cayo Blanco – Waterfront Commercial Opportunity in Front of the Vieques Ferry Terminal Located across from the ferry terminal in Isabel Segunda, Cayo Blanco offers one of the most high-visibility commercial locations available in Vieques, Puerto Rico real estate. This titled, mixed-use building was formerly operated as a popular bar, restaurant, and guesthouse, and is now ready for its next chapter. With daily foot traffic from both locals and tourists, sea views, and existing infrastructure, this is a prime investment opportunity in real estate in Puerto Rico—whether you’re planning a hospitality business, boutique hotel, or multi-use development. The first floor of the building includes an expansive open-air patio facing the Caribbean Sea—perfect for restaurant seating, live music, or sunset happy hours. This level previously served as a full-service bar and dining area, and offers plenty of indoor and outdoor space for a reimagined café, brewery, co-working space, or retail concept. With the ferry docks just steps away, every traveler arriving in or departing from Vieques passes right by the front door, making this one of the most enviable commercial footprints on the island. The second floor features a five-room guesthouse, each bedroom with a private en-suite bathroom and tiled flooring. The rooms are accessed by a wide, covered balcony that overlooks the water and the lively ferry activity below. With minimal updates, this level could be quickly refreshed and reopened for short-term vacation stays or longer-term accommodations—ideal for island visitors, business travelers, or even retreat attendees. The building is concrete construction and spans two full floors, making it a rare multi-unit opportunity in one of the most commercialized corridors of Vieques Island. Whether you're a hospitality veteran, investor, or entrepreneur, Cayo Blanco provides the platform to launch a business that capitalizes on both location and legacy. Vieques Island is one of the most sought-after destinations in the Puerto Rico real estate market. With its wild horses, laid-back culture, and spectacular natural beauty, the island draws tourists from around the world. From world-famous beaches like Playa Caracas and Playa Negra to the magical Bioluminescent Bay (BioBay)—one of the brightest in the world—Vieques offers unforgettable experiences that keep visitors returning year after year. The island’s culinary scene continues to expand, with restaurants like El Quenepo, Bili, Tin Box, and El Patio setting the bar for quality and creativity. Add in excellent snorkeling, wildlife preserves, and art galleries, and it’s easy to see why Vieques real estate for sale continues to gain traction. This property puts you at the center of it all. The foot traffic alone makes it a standout, but when combined with ocean views, proximity to transportation hubs, and mixed-use flexibility, Cayo Blanco becomes a truly exceptional listing in the Vieques Island real estate for sale category. If you’ve been searching for a commercial property for sale that offers immediate potential and long-term value, this is your opportunity. The structure is in place, the location is unmatched, and the zoning supports both hospitality and creative business models. With the right vision, Cayo Blanco could once again become a landmark venue on Vieques—and an anchor in the island’s growing economy. Contact us today to schedule a showing or request more information.